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Carmela Parenti Selected Research

Hyperalgesia

1/2021The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling.
5/2020Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists.
4/2020Lipid Nanoparticle Inclusion Prevents Capsaicin-Induced TRPV1 Defunctionalization.
11/2019Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain.
6/2016Harpagophytum procumbens extract potentiates morphine antinociception in neuropathic rats.
9/2015Involvement of the Heme-Oxygenase Pathway in the Antiallodynic and Antihyperalgesic Activity of Harpagophytum procumbens in Rats.
3/2014The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation.
2/2014Effects of a selective sigma 1 antagonist compound on inflammatory pain.
8/2013The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures.
4/2012Supraspinal injection of Substance P attenuates allodynia and hyperalgesia in a rat model of inflammatory pain.
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Carmela Parenti Research Topics

Disease

19Pain (Aches)
07/2021 - 07/2007
11Hyperalgesia
01/2021 - 07/2009
8Chronic Pain
04/2020 - 07/2009
6Neuralgia (Stump Neuralgia)
05/2022 - 08/2013
5Inflammation (Inflammations)
07/2017 - 07/2009
4Neoplasms (Cancer)
07/2019 - 01/2015
3Neuroblastoma
01/2019 - 01/2014
2Neurodegenerative Diseases (Neurodegenerative Disease)
02/2021 - 01/2014
2Neuroinflammatory Diseases
01/2021 - 01/2019
2Edema (Dropsy)
03/2014 - 02/2014
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
07/2017
1Lung Injury
07/2017
1Wilms Tumor (Wilm's Tumor)
05/2015
1Glioblastoma (Glioblastoma Multiforme)
01/2015
1Glioma (Gliomas)
01/2015
1Neurofibrosarcoma (MPNST)
01/2014
1Prostatic Neoplasms (Prostate Cancer)
05/2011

Drug/Important Bio-Agent (IBA)

11LigandsIBA
07/2021 - 05/2011
9Opioid Analgesics (Opioids)IBA
07/2021 - 04/2012
6Pharmaceutical PreparationsIBA
07/2021 - 01/2016
6CarrageenanIBA
09/2015 - 07/2009
5Opioid Receptors (Opioid Receptor)IBA
05/2022 - 06/2012
5Biological ProductsIBA
01/2016 - 07/2007
4Analgesics (Analgesic Drugs)IBA
07/2019 - 01/2012
3Connexin 43 (Connexin43)IBA
02/2021 - 10/2017
3NociceptinIBA
01/2012 - 07/2007
2CytokinesIBA
05/2022 - 01/2021
2delta Opioid Receptors (delta Opioid Receptor)IBA
05/2022 - 11/2019
2ConnexinsIBA
05/2022 - 02/2021
2mu Opioid Receptors (mu Opioid Receptor)IBA
12/2019 - 01/2012
2BenzomorphansIBA
11/2019 - 01/2012
2Proteins (Proteins, Gene)FDA Link
01/2019 - 01/2012
2ProdrugsIBA
10/2017 - 01/2015
2Haloperidol (Haldol)FDA LinkGeneric
10/2017 - 01/2015
2Morphine (MS Contin)FDA LinkGeneric
06/2016 - 01/2012
1Interleukin-6 (Interleukin 6)IBA
05/2022
1Ion Channels (Ion Channel)IBA
09/2020
1Lipid NanoparticlesIBA
04/2020
1Antidepressive Agents (Antidepressants)IBA
07/2019
1Norepinephrine (Noradrenaline)FDA LinkGeneric
07/2019
1Serotonin (5 Hydroxytryptamine)IBA
07/2019
1Duloxetine Hydrochloride (Cymbalta)FDA Link
07/2019
1Formaldehyde (Formol)FDA Link
03/2019
1Protein Isoforms (Isoforms)IBA
01/2019
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2019
1normetazocineIBA
03/2018
1Naloxone (Narcan)FDA LinkGeneric
03/2018
1Conditioned Culture MediaIBA
10/2017
1Neuroprotective AgentsIBA
10/2017
1Heme Oxygenase-1IBA
07/2017
1Oxygen (Dioxygen)IBA
07/2017
1Pulmonary Surfactants (Pulmonary Surfactant)IBA
07/2017
1AntioxidantsIBA
07/2017
1Reactive Oxygen Species (Oxygen Radicals)IBA
07/2017
1Fluoxetine (Prozac)FDA LinkGeneric
01/2017
1Transcription Factors (Transcription Factor)IBA
05/2015
1WT1 ProteinsIBA
05/2015
1Artificial Membranes (Artificial Membrane)IBA
01/2015
1Histone Deacetylase InhibitorsIBA
11/2014
11- (3',4'- dichloro- 2- fluoro(1,1'- biphenyl)- 4- yl)cyclopropanecarboxylic acidIBA
01/2014
1Substance PIBA
04/2012
1NeuropeptidesIBA
04/2012
1J 113397IBA
01/2012
1nocistatinIBA
01/2012
1(Nphe(1),Arg(14),Lys(15))N-OFQ NH(2)IBA
07/2009

Therapy/Procedure

2Ligation
01/2021 - 11/2019
2Analgesia
01/2019 - 04/2012
2Therapeutics
07/2017 - 01/2015
1Denervation
04/2020
1Injections
01/2012